Team Schedule: Detroit Lions
| Sept. 3 | at New Orleans | 1:00 p.m. |
| Sept. 10 | Washington | 4:15 p.m. |
| Sept. 17 | Tampa Bay | 1:00 p.m. |
| Sept. 24 | at Chicago | 1:00 p.m. |
| Oct. 1 | Minnesota | 1:00 p.m. |
| Oct. 8 | Green Bay | 1:00 p.m. |
| Oct. 15 | Bye Week | |
| Oct. 19 | at Tampa Bay | 8:20 p.m. |
| Oct. 29 | at Indianapolis | 1:00 p.m. |
| Nov. 5 | Miami | 1:00 p.m. |
| Nov. 12 | Atlanta | 1:00 p.m. |
| Nov. 19 | at New York Giants | 1:00 p.m. |
| Nov. 23 | New England | 12:30 p.m. |
| Nov. 30 | at Minnesota | 8:20 p.m. |
| Dec. 10 | at Green Bay | 1:00 p.m. |
| Dec. 17 | at New York Jets | 1:00 p.m. |
| Dec. 24 | Chicago | 1:00 p.m. |
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