| Buffalo Bills | |
| Date | Opponent | Time |
| Sept. 9 | New Orleans | 1:00 |
| Sept. 16 | at Miami | 1:00 |
| Sept. 23 | at Indianapolis | 1:00 |
| Sept. 30 | Pittsburgh | 1:00 |
| Oct. 7 | New York Jets | 4:05 |
| Oct. 14 | Bye | |
| Oct. 18 | at Jacksonville | 8:30 (Thu.) |
| Oct. 28 | at San Diego | 4:15 |
| Nov. 4 | Indianapolis | 4:15 |
| Nov. 11 | at New England | 1:00 |
| Nov. 18 | Seattle | 1:00 |
| Nov. 25 | Miami | 1:00 |
| Dec. 2 | at San Francisco | 8:30 |
| Dec. 9 | Carolina | 1:00 |
| Dec. 16 | New England | 1:00 |
| Dec. 23 | at Atlanta | 1:00 |
| Dec. 30 | at New York Jets | 1:00 |
Week 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
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