| Detroit Lions | |
| Date | Opponent | Time |
| Sept. 9 | at Green Bay | 1:00 |
| Sept. 16 | Dallas | 1:00 |
| Sept. 23 | at Cleveland | 1:00 |
| Sept. 30 | Bye | |
| Oct. 8 | St. Louis | 9:00 |
| Oct. 14 | at Minnesota | 1:00 |
| Oct. 21 | Tennessee | 1:00 |
| Oct. 28 | Cincinnati | 1:00 |
| Nov. 4 | at San Francisco | 4:05 |
| Nov. 11 | Tampa Bay | 1:00 |
| Nov. 18 | at Arizona | 4:15 |
| Nov. 22 | Green Bay | 12:30 (Thu.) |
| Dec. 2 | at Chicago | 1:00 |
| Dec. 9 | at Tampa Bay | 1:00 |
| Dec. 16 | Minnesota | 1:00 |
| Dec. 23 | at Pittsburgh | 1:00 |
| Dec. 30 | Chicago | 1:00 |
Week 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
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