But, pro football has had a plethora of brother vs. brother matchups through its history, all as players.
In fact, there are 348 documented sets of brothers who are and have played with and against each other, from the early pro leagues all the way to the current NFL, according to the Pro Football Hall of Fame.
Not all of them made this Top 10 list. At least one brother had to make it to the Hall of Fame to make this coveted bunch. That leaves out current quarterbacks Peyton and Eli Manning, and Mike and David Shula, sons of legendary coach Don Shula.
So, without further ado, here are the top pro football brother combinations.
1. Craig and Terry Bradshaw
2. Garland and "Red" Grange
"Red" was a celebrated halfback for the Chicago Bears and also played for the 1927 New York Yankees in their inaugural NFL season. Known as the "Galloping Ghost," Red was selected to the HOF in 1963. Garland played for Chicago from 1929-'31.
3. Jack and Jim Thorpe
The legendary Jim Thorpe, often called the "world's greatest athlete," played for several teams in a variety of pro football leagues in the 1920s before entering the HOF in 1963: Canton Bulldogs, Cleveland Indians, Oorang Indians, Rock Island Independents, New York Giants and Chicago Cardinals. He also played professional baseball and basketball and won two Olympic gold medals.
Jack played one year in 1923 for the Oorang Indians.
4. Phil, Orrin and Merlin Olsen
Merlin was a superb, All-Pro defensive tackle for the Los Angeles Rams and was selected to the HOF in 1982. Phil was also a defensive tackle, for the Rams and Broncos, while Orrin was a center who played one year for the 1976 Kansas City Chiefs. Merlin went on to have a television career, starring in "Little House on the Prairie" and "Father Murphy."
5. Dewey and Lee Roy Selmon
Lee Roy was a dominant defensive end with Tampa Bay and entered the HOF in 1995. He was named to Sports Illustrated's NCAA All-Century Football team. Dewey was also a linebacker, as well as a defensive tackle, for the Bucs and San Diego Chargers.
6. Clay and Bruce Matthews
Bruce was an offensive guard, center and tackle for Houston and Tennessee, making it to the HOF in 2007. He was also a 14-time Pro Bowl pick, a record he shares with Merlin Olsen. Clay was a linebacker for Cleveland and Atlanta. He had two sons who also played in the NFL.
7. Eddie and Walter Payton
Walter, known as "Sweetness," was an All-Pro running back for the Chicago Bears, and was elected to the HOF in 1993. He also holds the NFL record for touchdown passes from a non-quarterback with eight. Eddie was a kick returner and halfback for Cleveland, Detroit, Kansas City and Minnesota.
8. David and Larry Little
Larry was an offensive guard for the American Football League's San Diego Chargers and then for the Miami Dolphins in the AFL before they switched to the NFL. Little was not picked in the draft coming out of college, but he eventually entered the HOF in 1993. David played linebacker for the Pittsburgh Steelers.
9. George and Frank "Bruiser" Kinard
"Bruiser" played for the Brooklyn Dodgers and New York Yankees of the All-America Football Conference before being elected for the HOF in 1971. George played guard and linebacker for the Dodgers and Yankees as well.